Diabetes & Dogs! NSF Science Now 60

diabetes dogs and independence an engineering breakthrough in type 1 diabetes could help dogs and humans alike the disease affects about one in every 100 companion animals in the u.s. including dogs and cats and approximately 1.25 million American children and adults a multi-institution team of Purdue engineers with funding from the National Science Foundation is developing a new therapy that could replace the need for daily insulin injections for both canines and humans the therapy has the potential to reduce the number of shots to one shot every few months this breakthrough could make managing the disease much easier we rescued Lexie and we've had her for several years recently we've noticed that there are some different changes that she's had so we did take her to the doctor and found out that she has diabetes having to give her shots twice a day I have to constantly be thinking about where I am and what time and when I need to be home it does affect a lot if I could have it to where I wasn't having to worry about that every day it makes a tremendous change in my life in my family's life a preclinical animal study conducted collaboratively with the Indiana Center for diabetes and metabolic disease shows that the team's therapy is the first minimally invasive therapy to successfully reverse type one diabetes within 24 hours and maintain insulin independence for at least 90 days here's how it works the collagen formulation provides a new set of pancreatic cells to replace the clusters of cells called islets that aren't releasing insulin to monitor blood glucose levels the team is collaborating with Purdue's College of Veterinary Medicine to test their formula on dogs suffering from the disease we've completed preclinical animal testing and would like to work with pet owners in order to apply the cell therapy to dogs with diabetes with the ultimate goal of transitioning to humans with type 1 diabetes the results are promising so we are so excited and interested in move forward with dogs and human because of the preclinical testing that we saw where we saw almost and almost immediate lowering a blood glucose and maintenance of blood glucose for a prolonged period of time reading rewire is it possible to rewire for reading National Science foundation-funded researchers at the University of Washington have discovered that after several weeks of intensive instruction young participants who struggle with reading improve their skills by an average of one full grade level this reading growth was linked to changes in brain connectivity 24 children who ranged in age from 7 to 12 years took part in an intensive eight-week one-on-one reading intervention program as part of the study the participating children also took a series of diffusion MRI scans which measure the movement of water through brain tissue the scans are well suited for studying the changes in long range connections between different brain regions tissue known as white matter to determine what if any changes occurred in these connections the researchers documented rapid changes throughout an extensive network of white matter connections changes that track the participants growth in reading skills the team's findings demonstrate that targeted intensive reading programs not only lead to substantial improvement in reading skills but also change the underlining wiring of the brains reading circuitry hidden ice history the West Antarctic Ice Sheet or waves encompasses more than 6 million cubic miles of ice and could cause major sea level rise if it were to collapse but it's what's happening underneath the sheet that has researchers excited Mount Resnick a mile high in active volcano sitting beneath the ice sheet has created an almost six thousand year record of the ice sheets motion the data are providing new clues to past movement and overall behavior of a unique region in West Antarctica which unlike other areas that are thinning has been slowing down and thickening over the last few decades the record suggests that current localized the of the ice sheet is just a short-term event that may not affect the ice sheet over the long term the team says this is the first time they have seen a feature like this in West Antarctica while this is just one data set the team hopes to combine more radar scans to recreate a fuller picture of the history of the ice sheets motion they are quick to point out that the better we know the ice sheets past the more realistic we can be in predicting how the ice sheet will respond to future climate change for more information about these stories visit us at nsf.gov this is NSF science now I'm Dena Headlee you

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